Cruciferous Vegetables: Cancer Protective Mechanisms of Glucosinolate Hydrolysis Products and Selenium

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Cruciferous vegetables and colo-rectal cancer.

Cruciferous vegetables have been studied extensively for their chemoprotective effects. Although they contain many bioactive compounds, the anti-carcinogenic actions of cruciferous vegetables are commonly attributed to their content of glucosinolates. Glucosinolates are relatively biologically inert but can be hydrolysed to a range of bioactive compounds such as isothiocyanates (ITC) and indole...

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Selenium and Glucosinolates in Cruciferous Vegetables: Metabolic Interactions and Implications for Cancer Chemoprevention in Humans

Cancer is a leading cause of death in North America, and poor diet is suspected as a causative factor in 1/3 of all cancer deaths. Epidemiologic studies have shown that a diet rich in cruciferous vegetables such as broccoli is protective against many cancers. Broccoli contains sulforaphane (SI), a substance that activates promoter elements in certain phase II detoxification enzymes of animals, ...

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Glucosinolates from Cruciferous Vegetables for Cancer Chemoprevention

Prevention and/or protection against chemical carcinogens by phytochemicals present in extensively consumed glucosinolate-containing cruciferous vegetables is of great of interest, as they provide a safe and cost effective means of combating cancer. Extensive epidemiological studies revealed repeatedly an inverse relationship between cruciferous vegetable consumption and the incidence of cancer...

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A prospective study of cruciferous vegetables and prostate cancer.

High intake of cruciferous vegetables may offer some protection against prostate cancer, but overall data are inconclusive. Thus, we examined the association between cruciferous vegetable intake and risk of prostate cancer in the Health Professionals Follow-Up Study. Between 1986 and 2000, 2,969 cases of nonstage T1a prostate cancer were diagnosed in 47,365 men who completed dietary assessments...

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Intake of cruciferous vegetables modifies bladder cancer survival.

BACKGROUND Intake of cruciferous vegetables, a rich source of dietary isothiocyanates, has been inversely associated with risk of bladder cancer. Due to the potent antiproliferative effects of dietary isothiocyanates on bladder cancer in in vitro and in vivo models, cruciferous vegetable intake may also play a role in survival among patients with bladder cancer. METHODS Using information obta...

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ژورنال

عنوان ژورنال: Integrative Cancer Therapies

سال: 2004

ISSN: 1534-7354,1552-695X

DOI: 10.1177/1534735403261831